Precision nanoparticle technology enabling
a unique intranasal GLP-1

Direct-to-brain and less nausea. Next gen intranasal peptide therapeutics powered by our precision nanoparticle technology.

Our technology platform could potentially reduce nausea with high efficacy, and can be extended to other peptides and biologics

Our technology platform could potentially reduce nausea with high efficacy, and can be extended to other peptides and biologics

Precision nanoparticle technology enabling
a unique intranasal GLP-1

Direct-to-brain and less nausea. Next gen intranasal peptide therapeutics powered by our precision nanoparticle technology.

Our technology platform could potentially reduce nausea with high efficacy, and can be extended to other peptides and biologics

OPPORTUITY

GLP-1s are the most important
drug category of this century

GLP-1s are the most important
drug category of this century

PROBLEM

Over 50% of patients on GLP-1 injections get nauseous, and many more likely have needle fear

Despite GLP-1s proven benefits for weight loss and metabolic / cardiovascular health, many patients quit due to side effects

PLATFORM

A simple nasal spray to deliver the same drug with potentially similar efficacy but lower nausea

We target GLP-1 receptors in the olfactory region responsible for appetite, with animal data showing lower systemic exposure and vomiting

OPPORTUNITY

This is the largest drug in biotech, likely to exceed $100B in a few years

Besides obesity, the nose-to-brain (N2B) delivery could potentially enable other neurological indications such as addiction or dementia, and be used to encapsulate other therapeutic agents.

RESEARCH

We bring 30+ years of biomedical innovation from Columbia University to improve drug delivery for a variety of indications.

EXPLORE OUR RESEARCH

EXPLORE OUR RESEARCH

Drug and gene delivery

Nonviral Gene Editing

Nanotherapeutics manufacturing

Biomaterials for regenerative medicine

Robin Guo

CEO & Co-Founder

If we can help solve the obesity crisis because we lower the nauseating side effects of this miracle drug, that is a mission I can dedicate my life to.

Latest in GLP-1s, biohacking, and peptides

Bi-weekly insights on the fast changing peptide space that's scientifically grounded

READ MORE

READ MORE

Latest in GLP-1s, biohacking, and peptides

Bi-weekly insights on the fast changing peptide space that's scientifically grounded

READ MORE

Our Investors

Sam Shank

Sam Shank

Founder, Hotel Tonight

Kevin Lin

Kevin Lin

co-founder, twitch

Nate Mitchell

co-founder, Oculus

Kevin Lin
Founder,
Twitch

Disclaimer

The information on this website relates to early-stage, preclinical research and is intended for scientific and informational purposes only. Findings described here are based on studies conducted in animal models and have not been evaluated in human clinical trials. These results may not translate to humans. Nothing on this site is intended to diagnose, treat, cure, or prevent any disease, and no claims are made regarding the safety or efficacy of any product, therapy, or technology in humans. Any statements about potential applications are exploratory and forward-looking, not guarantees of future results.This content has not been evaluated by the FDA or any other regulatory body, and no product referenced here is approved for human use or commercially available. Statements on this website should not be construed as medical advice, investment advice, or an offer to sell any product or service.

DISCLAIMER

The information on this website relates to early-stage, preclinical research and is intended for scientific and informational purposes only. Findings described here are based on studies conducted in animal models and have not been evaluated in human clinical trials. These results may not translate to humans. Nothing on this site is intended to diagnose, treat, cure, or prevent any disease, and no claims are made regarding the safety or efficacy of any product, therapy, or technology in humans. Any statements about potential applications are exploratory and forward-looking, not guarantees of future results.This content has not been evaluated by the FDA or any other regulatory body, and no product referenced here is approved for human use or commercially available. Statements on this website should not be construed as medical advice, investment advice, or an offer to sell any product or service.